Presented at Los Alamos IEEE Section Luncheon, June 15, 1999

Optical tomography: seeing inside the body

Kenneth M. Hanson
Los Alamos National Laboratory


The passage of infrared light through biological tissue is essentially a diffusion process. Our goal is to reconstruct the diffusion coefficients inside a volume of tissue. Light pulses are incident onto a volume, and light intensity measurements are taken of the time-dependent responses around the surface of that volume. The analysis is a difficult problem. Our approach is to invert the diffusion equation by using a numerical technique called adjoint differentiation. This technique is generally applicable to deterministic problems that can be modeled numerically by simulation computer codes.


Keywords: optical tomography, diffusion of infrared light, adjoint differentiation, inversion of numerical simulations

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